New Work For
An Old Tooth Fairy

Out of the mouths of babes shall come wisdom and healing

by Lin Stone

Small children have suffered from financial privation over the past few years because the number of career-oriented tooth fairies has steadily declined. It used to be that kids were satisfied with finding a dime or a quarter under their pillow from the tooth fairy. Savage inflation has made the value of a dime so pitiful it won't even buy as much as a penny used to. Low tooth prices aren't just caused by inflation though. Those Tooth Fairies still in the business have experienced severe downturns in the resale market as well. “Who needs a used tooth?”

That may be about to change.

It is now known that primary teeth from young children are an excellent source for adult stem cells. In fact, research is showing primary teeth might soon be used to treat a growing number of severe illnesses including cancer and heart disease. A few Tooth Fairies have been lucky enough to uncover a new company that has been founded to provide preservation service for stem cells, using primary teeth plucked from beneath the pillow of young children.

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 “The BioEden, Inc. Baby Teeth Cell Bank out of Austin Texas is the first company of its kind anywhere in the world.” According to President Jeff Johnson, “Stem cell research is the most promising path to curing many severe diseases and disabling medical conditions. For stem cell therapy to work, however, it is imperative that the source of the stem cells be compatible with each recipient.”

BioEden, is NOT a public cell bank like umbilical cord blood banks. “What we do is isolate and store cells and then return the teeth to the original donor to keep just in case they are ever needed.”

That makes sense. By maintaining immaculate control of storage for the cells you won't have to worry about communicable diseases, tissue rejection, or even having to undergo immunosuppressive therapy. “If children ever have a need for the stem cells from their primary teeth they will get their own cells back -- and nothing else.”

According to President Johnson, Dr. Songtao Shi, Principle Investigator of the Dental Biology Unit at the National Institute of Health identified adult stem cells in primary children's teeth back in 2003. “Actually, it all started back in 2000 when Dr. Songtao Shi and Dr. Stan Gronthos discovered stem cells inside adult teeth.” The next time his daughter lost a tooth, Dr. Shi was ready. He rushed her tooth to the lab and extracted the pulp. First he broke it apart into individual cells then placed those cells in a Petri dish with culture medium. After incubating the dish in a hot, humid environment -- with plenty of oxygen -- some of the tooth cells started to grow. Subsequent tests have shown that baby-tooth cells behaved like stem cells. “They multiplied rapidly, they stayed alive in culture for months, and they could differentiate into nerve-like cells, dentin, bone, and fat cells.
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Better news was coming. “When transplanted into mice, the cells grew into tooth like structures (although they lacked the hard enamel covering of real teeth). The Progenitor cells discovered include adiposites, osteoblasts, chondracytes, and mesenchymal stem cells.” These types of cells are all being investigated for their ability to therapeutically treat many human diseases including heart disease, bone regeneration, and most promisingly neuronal degenerative disorders such as Alzheimer's, Parkinson's, and even spinal cord injury.

However, it is critical that these cells be extracted quickly after the tooth falls out. Therefore, speed is of the essence. Enter the Tooth Fairy with a role more important than any held before in history because most children only have twelve teeth that can be used for this process. More importantly, not every tooth picked up by the Tooth Fairy will contain cells with this potential.

BioEDEN, is providing this assistance at an affordable price. Here's how it works. “When your child's tooth begins to loosen, the tooth fairy can call us. We will send out a kit with processing instructions, and make arrangements to have the tooth transported to our facility in Austin, Texas. There the cells contained in the tooth will be removed and stored in a special process that keeps them viable for the future.”

Even the old tooth fairies know that world health care is now moving toward personalized medicine where treatments are customized for each individual.  The use of stem cells found in children's primary teeth to treat debilitating conditions is a significant step toward that goal. Best of all, this particular version of taking stem cells from children's primary teeth is being applauded instead of condemned.

President Johnson says: “The process is proving to be a morally non-controversial alternative to the possibilities offered by embryonic stem cells.”

Yes, BioEden is registered with the FDA, and it is the first fully-operational processing laboratory and storage bank for primary teeth stem cells to open in the U.S. Their state-of-the-art facilities are located in Austin, Texas, and will serve children and their families nationwide. BioEden is also the only cell storage facility willing to guarantee their services.

the end

If you know an old tooth fairy about to go out of business you might show them how to find this article.

Journalists can contact Dr. Songtao Shi: at:
NATIONAL INSTITUTES OF HEALTH/NIDCR
BUILDING 30 ROOM 222
30 CONVENT DR MSC 4320
BETHESDA MD 20892-4320
Phone: (301) 435-4584
Fax: (301) 402-0824

The latest contact information for President Johnson can be found at http://www.bioeden.com   

To research this subject even further you might want to study:
Christopher Nosrat, DDS, Ph.D.:
Assistant Professor of Biological and Materials Sciences Room D3218 Dentistry
University of Michigan School of Dentistry
Dept. of Biologic & Materials Sciences
Division of Prosthodontics
1011 North University Avenue
Ann Arbor MI 48109-1078
Phone: (734) 615-4388

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About the author:  Independently less than wealthy, Lin Stone has some of his best writing appearing on the following sections of Insurance Roundup Roundup: Acne Before Christmas  Save Big Money On EVERYTHING You Should Insure  *  Allergies Can Kill You  *  Bargains For Budding Millionaires  *  Some Uncanny Cancer Cures  *  and Easy Crafts Do Make  Wonderful Gifts  *